Michael Scholl
Animation of the cortical spreading depression
Image by User:S. Jähnichen Brain_bulbar_region.svg: Image:Brain human sagittal section.svg by Patrick J. Lynch; Image:Brain bulbar region.PNG by DO11.10; present image by Fvasconcellos., via Wikimedia Commons. Licensed CC BY 2.5

Michael Scholl

Cortical spreading depression Cortical spreading depression Type of evoked potential Cortical spreading depression (CSD) or spreading depolarization (SD) is a wave of electrophysiological hyperactivity followed by a wave of inhibition.[3] Spreading depolarization describes a phenomenon characterized by the appearance of depolarization waves of the neurons and neuroglia[4] that propagates across the cortex at a velocity of 1.5–9.5 mm/min.[5][6][7][8] Animation of cortical spreading depression Cortical spreading depression seen using intrinsic optical signal imaging in gyrencephalic brain. Speed 50x.[1] Hemodynamic changes observed after MCA occlusion in IOS. The video has a speed of 50x to better appreciate the SDs through human eye. Pictures are dynamically subtracted to a reference picture 40 s before. First we see the initial area of change at…

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Each Time I Close My Eyes / Laugh Clown Laugh
Each Time I Close My Eyes / Laugh Clown Laugh (1969)